New Schiff Base-Linked Arylazopyrazoles as Reagents for the Photometric Detection of Fluoride Ions

A novel class of reagents (L1-3) containing arylazopyrazole moiety linked to a Schiff base have been synthesized and investigated for anion sensing applications. All three compounds exhibited excellent sensitivity and selectivity toward selective colorimetric detection of F.sup.- in dimethyl sulfoxide. F.sup.- sensing mechanisms have been explored by various spectroscopic techniques, viz., .sup.1H NMR, IR, UV-visible, and fluorescence spectroscopy. A clear qualitative and quantitative detection of F.sup.- was possible with specificity and good sensitivity with L2 giving optimum results. The LOD value of L2 toward F.sup.- was found to be 7 [micro]M. These reagents were applied for fluoride detection in commercial toothpaste as well.
Author(s): Manish Kumar [sup.1] , Harshawardhan Agarkar [sup.2] , Mariam S. Degani [sup.1] Author Affiliations: (1) grid.479974.0, 0000 0004 1804 9320, Department of Pharmaceutical Sciences and Technology, Institute of Chemical [...]