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Inhibition of NF-kB by S-nitrosylation

Authors :
Marshall, Harvey E.
Stamler, Jonathan S.
Source :
Biochemistry. Feb 13, 2001, Vol. 40 Issue 6, p1688, 6 p.
Publication Year :
2001

Abstract

Results show that S-nitrosylation inhibits the transcriptional activator NF-kB in vivo within the nucleus. Data further indicate that cellular NF-kB activity is regulated by p50 nitrosylation via inhibition of p50 binding to DNA .

Subjects

Subjects :
Genetic transcription -- Regulation
Enzyme activation -- Analysis
Enzymes -- Regulation
Biological sciences
Chemistry

Details

ISSN :
00062960
Volume :
40
Issue :
6
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.71843925

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