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Potential Role of the Early Response Gene c-myc in Β-Cell Adaptation to Changes in Glucose Concentration

Authors :
Jonas, Jean-Christophe
Laybutt, Ross
Steil, Garry M.
Trivedi, Nitin
Weir, Gordon C.
Henquin, Jean-Claude
Source :
Diabetes. February 2001, Vol. 50 Issue 2, S137
Publication Year :
2001

Abstract

Type 2 diabetes is characterized by a reduction in both insulin sensitivity and glucose-stimulated insulin secretion (GSIS). Although insulin resistance usually precedes Β-cell dysfunction, the role of the latter in [...]

Details

Language :
English
ISSN :
00121797
Volume :
50
Issue :
2
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.71185874