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Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

Authors :
Kamisago, Mitsuhiro
Sharma, Sapna D.
DePalma, Steven R.
Solomon, Scott
Sharma, Pankaj
McDonough, Barbara
Smoot, Leslie
Mullen, Mary P.
Woolf, Paul K.
Wigle, E. Douglas
Seidman, J.G.
Seidman, Christine E.
Source :
The New England Journal of Medicine. Dec 7, 2000, Vol. 343 Issue 23, p1688, 9 p.
Publication Year :
2000

Abstract

Mutations in the genes for some proteins in heart muscle may cause some types of cardiomyopathy. Cardiomyopathy is the medical term for heart disease that does not involve the coronary arteries or heart valves. This study of five families shows that cardiomyopathy may be a muscle defect.

Details

ISSN :
00284793
Volume :
343
Issue :
23
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.67874919