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Modeling Immune Evasion and Vaccine Limitations by Targeted Nasopharyngeal Bordetella pertussis Inoculation in Mice

Authors :
Soumana, Illiassou Hamidou
Linz, Bodo
Dewan, Kalyan K.
Sarr, Demba
Gestal, Monica C.
Howard, Laura K.
Caulfield, Amanda D.
Rada, Balazs
Harvill, Eric T.
Source :
Emerging Infectious Diseases. August, 2021, Vol. 27 Issue 8, p2107, 10 p.
Publication Year :
2021

Abstract

Less than a century ago, Bordetella pertussis was rampant worldwide, causing pertussis (whooping cough) that killed millions of persons every year, mostly infants and children (1). Whole-cell pertussis vaccines (wP), [...]

Details

Language :
English
ISSN :
10806040
Volume :
27
Issue :
8
Database :
Gale General OneFile
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsgcl.670208089
Full Text :
https://doi.org/10.3201/eid2708.203566