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Post-acute COVID-19 syndrome
- Source :
- Nature Medicine. April, 2021, Vol. 27 Issue 4, p601, 15 p.
- Publication Year :
- 2021
-
Abstract
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in global healthcare crises and strained health resources. As the population of patients recovering from COVID-19 grows, it is paramount to establish an understanding of the healthcare issues surrounding them. COVID-19 is now recognized as a multi-organ disease with a broad spectrum of manifestations. Similarly to post-acute viral syndromes described in survivors of other virulent coronavirus epidemics, there are increasing reports of persistent and prolonged effects after acute COVID-19. Patient advocacy groups, many members of which identify themselves as long haulers, have helped contribute to the recognition of post-acute COVID-19, a syndrome characterized by persistent symptoms and/or delayed or long-term complications beyond 4 weeks from the onset of symptoms. Here, we provide a comprehensive review of the current literature on post-acute COVID-19, its pathophysiology and its organ-specific sequelae. Finally, we discuss relevant considerations for the multidisciplinary care of COVID-19 survivors and propose a framework for the identification of those at high risk for post-acute COVID-19 and their coordinated management through dedicated COVID-19 clinics. A comprehensive review of the current literature on post-acute COVID-19, also referred to as long COVID, its pathophysiology and its organ-specific sequelae highlights the need for multidisciplinary follow-up and care of COVID-19 survivors.<br />Author(s): Ani Nalbandian [sup.1] , Kartik Sehgal [sup.2] [sup.3] [sup.4] , Aakriti Gupta [sup.1] [sup.5] [sup.6] , Mahesh V. Madhavan [sup.1] [sup.5] , Claire McGroder [sup.7] , Jacob S. Stevens [...]
- Subjects :
- Biological sciences
Health
Subjects
Details
- Language :
- English
- ISSN :
- 10788956
- Volume :
- 27
- Issue :
- 4
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.658607760
- Full Text :
- https://doi.org/10.1038/s41591-021-01283-z