Current therapies under investigation for COVID-19: potential COVID-19 treatments

In response to the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), researchers are expeditiously searching for antiviral treatments able to alleviate the symptoms of infection, which can be life-threatening. Here, we provide a general overview of what is currently known about the structure and characteristic features of SARS-CoV-2, some of which could potentially be exploited for the purposes of antiviral therapy and vaccine development. This minireview also covers selected and noteworthy antiviral agents/supportive therapy out of hundreds of drugs that are being repurposed or tested as potential treatments for COVID-19, the disease caused by SARS-CoV-2. Key words: COVID-19, coronavirus, SARS-CoV-2, SARS-CoV, MERS-CoV. En reaction a flambee de nouveau coronavirus du syndrome respiratoire aigu severe (SARS-CoV-2), les chercheurs se sont mis de maniere expeditive a la recherche de traitements antiviraux permettant d'attenuer les symptomes de l'infection, lesquels pouvant menacer le pronostic vital. Nous proposons ici un apercu general de ce que l'on sait en ce moment de la structure et des caracteristiques du SARS-CoV-2, dont certaines pourraient etre exploitees en vue du developpement de traitements antiviraux et de vaccins. Cette courte synthese couvre aussi des agents antiviraux et des traitements de soutien selectionnes et dignes de mention parmi des centaines de medicaments en voie d'etre reconvertis ou testes comme traitements eventuels contre la COVID-19, la maladie causee par le SARS-CoV-2. [Traduit par la Redaction] Mots-cles : COVID-19, coronavirus, SARS-CoV-2, SARS-CoV, MERS-CoV.
SARS-CoV-2 A newly emerged human coronavirus, called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) (formerly named 2019-nCoV), was first reported in Wuhan, China. It belongs to the Baltimore Group IV [...]