Overexpression of the RNA polymerase alpha subunit reduces transcription of Bvg-activated virulence genes in Bordetella pertussis

Authors :: Carbonetti, Nicholas H.
Romashko, Alla
Irish, Teresa J.
Source :: Journal of Bacteriology. Jan, 2000, Vol. 182 Issue 1-2, p529, 3 p.
Publication Year :: 2000
Abstract: Research has been conducted on the RNA polymerase alpha subunit in Bordetella pertussis. Results indicate that overexpression of this RNA polymerase reduces expression of the virulence factor pertussis toxin at the transcription level.

Subjects :: Bacteriology -- Research
Gene expression -- Research
RNA polymerases -- Research
Genetic transcription -- Research
Virulence (Microbiology) -- Analysis
Bordetella pertussis -- Research
Toxins -- Research
Biological sciences

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