Severe Hyperlipidemia and Increased Lipid Synthesis Rates Associated with Resistance of Lipoproteins to Oxidative Modification in Glucose-6-Phosphatase Deficient Patients

Authors :: BANDSMA, ROBERT H. J.
RAKE, JAN-PETER
SMIT, PETER G. A.
PRINCEN, HANS M. G.
NEESE, RICHARD A.
HELLERSTEIN, MARC K.
KUIPERS, FOLKERT
Source :: Diabetes. May, 2000, Vol. 49 Issue 5, A293
Publication Year :: 2000
Abstract: Glucose-6-phosphatase (G-6-Pase) is a key enzyme in hepatic glucose metabolism and its activity is increased in diabetic states. Deficiency of G-6-Pase activity in Glycogen Storage Disease type I (GSD-I) leads [...]

Subjects :: Glucose metabolism -- Physiological aspects
Glycogenosis -- Physiological aspects
Hypercholesterolemia -- Physiological aspects
Diabetes -- Research
Comorbidity -- Research
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