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Enhanced Protein O-GLcNAcylation Is Associated with Insulin Resistance in GLUT1 Overexpressing Mouse Muscle

Authors :
BUSE, MARIA
ROBINSON, KATY
MARSHALL, BESS
HRESKO, RICHARD
MUECKLER, MIKE
Source :
Diabetes. May, 2000, Vol. 49 Issue 5, A58
Publication Year :
2000

Abstract

O-linked glycosylation on Ser/Thr with single N-acetyiglucosamine (O-GlcNAcylation) is a reversible modification of many cytoplasmic and nuclear proteins, regulated in part by UDP-N-acetylglucosamine (UDP-GlcNAc) levels. Transgenic (T) mice that overexpress [...]

Details

ISSN :
00121797
Volume :
49
Issue :
5
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.62891470