C677T Mutation of Methylenetetrahydrofolate Reductase Is an Independent Risk Determinant of Coronary Artery Calcification in Type 2 Diabetic Patients

Authors :: HOSOI, MASAYUKI
SATO, TOSHIHIKO
YAMAGAMI, KEIKO
KAIBARA, AYA
TSUJI, NOZOMI
YAMAMOTO, TSUNEHIKO
YAMAKITA, TETSUYA
MIYAMOTO, MASAFUMI
FUJII, SATORU
Source :: Diabetes. May, 2000, Vol. 49 Issue 5, A54
Publication Year :: 2000
Abstract: Plasma homocysteine levels are established to linked to ischemic heart disease, which is a pivotal complication for diabetic patients. The enzyme methylenetetrahydrofolate reductase (MTHFR) is involved in the folate-dependent remethylation [...]

Subjects :: Atherosclerosis -- Risk factors
Type 2 diabetes -- Health aspects
Coronary arteries -- Obstruction
Arteries -- Calcification
Health

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