A common pharmacophore for Taxol and the epothilones based on the biological activity of a taxane molecule lacking a C-13 side chain

Authors :: He, Lifeng
Jagtap, Prakash G.
Kingston, David G.I.
Shen, Heng-Jia
Orr, George A.
Horwitz, Susan Band
Source :: Biochemistry. April 11, 2000, Vol. 39 Issue 14, p3972, 7 p.
Publication Year :: 2000
Abstract: Research has been conducted on Taxol. The study of Taxol structure and activity has indicated the existence of the side chain at C-13.

Subjects :: Biochemistry -- Research
Taxol -- Research
Microtubules -- Research
Cells -- Analysis
Biological sciences
Chemistry

Tools