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Impaired Insulin Secretion Due to a Defect in Exocytosis in Heterozygous PDX-1 Deficient Mice
- Source :
- Diabetes. May, 2000, Vol. 49 Issue 5, A44
- Publication Year :
- 2000
-
Abstract
- The transcription factor PDX-1 is critical for pancreatic development and in regulating expression of beta-cell specific genes, including the insulin gene. Humans and mice lacking one allele of the PDX-1 [...]
Details
- ISSN :
- 00121797
- Volume :
- 49
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Diabetes
- Publication Type :
- Periodical
- Accession number :
- edsgcl.62891413