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Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding

Authors :
Visco, Carlo
Magistrelli, Giovanni
Bosotti, Roberta
Perego, Rita
Rusconi, Luisa
Toma, Salvatore
Zamai, Moreno
Acuto, Oreste
Isacchi, Antonella
Source :
Biochemistry. March 14, 2000, Vol. 39 Issue 10, p2784, 8 p.
Publication Year :
2000

Abstract

Research has been conducted on the protein tyrosine kinase ZAP-70. The binding of ZAP-70 to the phosphorylated immunoreceptor tyrosine-based activation motifs of the T-cell antigen receptor is described.

Details

ISSN :
00062960
Volume :
39
Issue :
10
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.62856034