Reexamining the Prevalence of Chlamydia trachomatis Infection Among Gay Men With Urethritis

Background: Evidence of an STD-HIV interaction and the availability of noninvasive urine-based screening tests have resulted in an increased focus on chlamydial infections in men. Goal: To evaluate the prevalence of chlamydial infections among men with urethritis at the San Francisco City Clinic (SFCC). Study Design: In 1997, male SFCC patients diagnosed with urethritis were tested for chlamydia using urine-based ligase chain reaction and for gonorrhea using urethral culture. Results: Gonorrhea was identified in 45% of men who have sex with men (MSM) versus 26% of men who have sex with women (MSW). Among men with gonorrhea, chlamydia coinfection was found among 15.2% of MSM and 8.4% of MSW. Among men with nongonococcal urethritis, 18% and 20% of MSM and MSW had chlamydial infection, respectively. Young age was associated with chlamydial infection in MSM. Conclusion: After a period of low chlamydiai infection rates in MSM during the pre-AIDS era, infection rates are increasing among this population. SFCC's revised clinical practice guidelines include chlamydia testing of MSM with urethritis.
More and more gay men are becoming infected with chlamydia, which is a sexually transmitted disease. It can occur in conjunction with other STDs, such as gonorrhea and non-gonococcal urethritis.