Differential Activation of Peroxisome Proliferator-Activated Receptor-[Gamma] by Troglitazone and Rosiglitazone

Authors :: Camp, Heidi S.
Li, Ou
Wise, Scott C.
Hong, Yu H.
Frankowski, Christy L.
Shen, Xi-qiang
Vanbogelen, Ruth
Leff, Todd
Source :: Diabetes. April 2000, Vol. 49 Issue 4, 539
Publication Year :: 2000
Abstract: The antidiabetic thiazolidinediones, which include troglitazone and rosiglitazone, are ligands for the nuclear receptor peroxisome proliferator-activated receptor (PPAR)-[Gamma] and exert their antihyperglycemic effects by regulation of PPAR-[Gamma]-responsive genes. We report [...]

Subjects :: Avandia (Medication) -- Physiological aspects
Troglitazone -- Physiological aspects
Hypoglycemic agents -- Physiological aspects
Thiazolidinediones -- Physiological aspects
Type 2 diabetes -- Drug therapy
Health
Drug therapy
Physiological aspects

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