A mechanistic study of the Horner-Wadsworth-Emmons reaction: computational investigation on the reaction pass and the stereochemistry in the reaction of lithium enolate derived from trimethyl phosphonoacetate with acetaldehyde

Authors :: Ando, Kaori
Source :: Journal of Organic Chemistry. Sept 3, 1999, Vol. 64 Issue 18, p6815, 7 p.
Publication Year :: 1999
Abstract: Research has been conducted on the mechanism of the Horner-Wadsworth-Emmons (HWE) reaction. Results indicate that HWE reaction of lithium enolate occurs with the addition of lithium enolate to aldehyde.

Subjects :: Chemistry, Organic -- Research
Stereochemistry -- Research
Lithium -- Research
Aldehydes -- Research
Biological sciences
Chemistry

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