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A new peak in the ALPS

Authors :
Fischer, Alain
Rieux-Laucat, Frederic
Le Deist, Francoise
Source :
Nature Medicine. August, 1999, Vol. 5 Issue 8, p876, 2 p.
Publication Year :
1999

Abstract

One form of autoimmune lymphoproliferative syndrome II (ALPS II) involves a mutation in the gene for CASP 10. CASP 10 is involved in lymphocyte apoptosis, and the resulting defect in apoptosis causes an abnormal accumulation of T and B cells and autoimmune disease.

Details

ISSN :
10788956
Volume :
5
Issue :
8
Database :
Gale General OneFile
Journal :
Nature Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.59220732