Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment

Authors :: Meininger, David P.
Rance, Mark
Starovasnik, Melissa A.
Fairbrother, Wayne J.
Skelton, Nicholas J.
Source :: Biochemistry. Jan 11, 2000, Vol. 39 Issue 1, p26, 11 p.
Publication Year :: 2000
Abstract: A study of the 32-kDa complex formed between an E-domain mutant and Fv-fragment of the humanized anti-HER2 antibody is presented. Results characterize the interface formed by SpA repeats.

Subjects :: Biochemistry -- Research
Proteins -- Research
Staphylococcus -- Research
Mutation (Biology) -- Research
Biological sciences
Chemistry

Tools