Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenopathy in men with node-positive prostate cancer

Therapy to suppress male sex hormones appears to be beneficial for men with prostate cancer who have had their prostate removed. Sex hormones can often stimulate cancers. Researchers randomly assigned 98 men with prostate cancer who had their prostate removed to have anti-androgen therapy or no further treatment. At the last follow-up, 77% of the men who received anti-androgen therapy were alive and well compared to 18% of the men who did not. Men who received anti-androgen therapy were also less likely to have a relapse.