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-Lipoic Acid: Effect on Glucose Uptake, Sorbitol Pathway, and Energy Metabolism in Experimental Diabetic Neuropathy

Authors :
Kishi, Yutaka
Schmelzer, James D.
Yao, Jeffrey K.
Zollman, Paula J.
Nickander, Kim K.
Tritschler, Hans J.
Low, Phillip A.
Source :
Diabetes. October 1999, Vol. 48 Issue 10, 2045
Publication Year :
1999

Abstract

The peripheral nerve of experimental diabetic neuropathy (EDN) is reported to be ischemic and hypoxic, with an increased dependence on anaerobic metabolism, requiring increased energy substrate stores. When glucose stores [...]

Details

Language :
English
ISSN :
00121797
Volume :
48
Issue :
10
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.56456905