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Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia

Authors :
Talley, Nicholas J.
Vakil, Nimish
Ballard, E. David, II
Fennerty, M. Brian
Source :
The New England Journal of Medicine. Oct 7, 1999, Vol. 341 Issue 15, p1106, 6 p.
Publication Year :
1999

Abstract

Eradicating Helicobacter pylori does not appear to cure dyspepsia. Dyspepsia is the medical term for heartburn. It can sometimes be caused by an ulcer. Helicobacter pylori is a bacterium that has been linked to ulcer formation. Researchers randomly assigned 170 patients with Helicobacter pylori infection and dyspepsia not caused by an ulcer to receive treatment for the infection or a placebo for 14 days. The bacterium was eradicated in 90% of the patients who received the treatment compared to 2% of the placebo group. However, both groups continued to have symptoms of dyspepsia.

Details

ISSN :
00284793
Volume :
341
Issue :
15
Database :
Gale General OneFile
Journal :
The New England Journal of Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.56076141