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The crystal structure of exfoliative toxin B: a superantigen with enzymatic activity
- Source :
- Biochemistry. August 10, 1999, Vol. 38 Issue 32, p10239, 8 p.
- Publication Year :
- 1999
-
Abstract
- The exfoliative toxins (ETs) cause staphylococcal scalded skin syndrome, a disease characterized by specific separation of layers of the skin. Research has shown that the toxins act as serin proteases, though the specific substrate and mode of action are not known for certain. The crystal structure of exfoliative toxin A (ETA) has been found previously to be similar to that of chymotrypsin-like serine proteases. The 2.4 angstrom resolution crystal structure of the other exfoliative toxin, ETB, which is 40% identical to ETA.
Details
- ISSN :
- 00062960
- Volume :
- 38
- Issue :
- 32
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.55728192