A simple and short synthesis of divinyl cholorophyll derivatives

The effects of substituents in the benzobacteriochlorin series was investigated by preparing and evaluating the biological activity of the hexyl ether derivative. A chlorophyll biosynthetic intermediate was successfully synthesized, which was then extended to the preparation of another biosynthetic intermediate, methyl 3,8-divinylpheophorbide alpha. The results showed that the synthetic procedure developed provided the preparation of the target compound in the fewest steps possible, avoiding wasteful yield losses and minimizing synthesis time.