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Akt-1 Activation is Required for Insulin Stimulation of Glycogen Synthesis, p85S6Kinase Phosphorylation, Protein Synthesis but not for Glucose Transport in 3T3-L1 Adipocytes

Authors :
SHARMA, PREM M
SON, HYUN-SHIK
EGAWA, KATUSYA
NELSON, JAY
SUMMERS, SCOTT
BIRNBAUM, MORRIS J
ROSE, DAVID W
Source :
Diabetes. May, 1999, Vol. 48 Issue 5, SA221
Publication Year :
1999

Abstract

A wide variety of biological activities including the major metabolic actions of insulin are regulated by PI3-kinase. However, the downstream effectors of the various signaling pathways that emanate from PI [...]

Subjects

Subjects :
Diabetes -- Research
Health

Details

ISSN :
00121797
Volume :
48
Issue :
5
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.54771220