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Serine-Threonine Phosphorylation and Degradation of IRS-1 in Insulin Resistant States: Mechanisms and Prevention

Authors :
RONDINONE, CRISTINA M.
PEDERSON, TERRY
Source :
Diabetes. May 1999, Vol. 48 Issue 5, SA220
Publication Year :
1999

Abstract

We have demonstrated that IRS-1 protein expression is markedly reduced in adipocytes from NIDDM subjects in comparison with both healthy and IDDM individuals although the mechanisms for this reduction were [...]

Details

Language :
English
ISSN :
00121797
Volume :
48
Issue :
5
Database :
Gale General OneFile
Journal :
Diabetes
Publication Type :
Periodical
Accession number :
edsgcl.54771219