Genetic mapping of ossification of the posterior longitudinal ligament of the spine

Authors :: Koga, Hiroaki
Sakou, Takashi
Taketomi, Eiji
Hayashi, Kyouji
Numasawa, Takuya
Harata, Seiko
Yone, Kazunori
Matsunaga, Shunji
Otterud, Brith
Inoue, Ituro
Leppert, Mark
Source :: American Journal of Human Genetics. June, 1998, Vol. 62 Issue 6, p1460, 8 p.
Publication Year :: 1998
Abstract: Ossification of the posterior longitudinal ligament of the spine (OPLL) has been mapped to a predisposing locus on chromosome 6p close to the HLA complex. A genetic-linkage study has been carried out in 91 affected sib pairs from 53 Japanese families. OPPLL is a common disorder among Japanese people and all over Asia.

Subjects :: Asia -- Health aspects
Ossification -- Genetic aspects
Genetic disorders -- Research
Chromosome mapping -- Usage
Spine -- Abnormalities
Biological sciences

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