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Linkage analysis of X-linked cone-rod dystrophy: localization to Xp11.4 and definition of a locus distinct from RP2 and RP3

Authors :
Seymour, Albert B.
Dash-Modi, Anita
O'Connell, Jeffrey R.
Shaffer-Gordon, Maria
Mah, Tammy S.
Stefko, S. Tonya
Nagaraja, Ramaiah
Brown, Jeremiah
Kimura, Alan E.
Ferrell, Robert E.
Gorin, Michael B.
Source :
American Journal of Human Genetics. Jan, 1998, Vol. 62 Issue 1, p122, 8 p.
Publication Year :
1998

Abstract

A linkage analysis of X-linked cone-rod dystrophy (COD1) has narrowed the locus to a limited section of Xp11.4, distal to DXS993 and proximal to DXS556, a length of about 1.0 Mb. The locus is well enough defined for positional cloning. The results also show that the COD1 gene cannot be an allelic variant of RP3, a gene for retinitis pigmentosa.

Details

ISSN :
00029297
Volume :
62
Issue :
1
Database :
Gale General OneFile
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
edsgcl.54409827