Self-association patterns of sodium taurocholate and taurodeoxycholate as studied by frontal derivative chromatography

Research was conducted to examine the aggregation patterns of sodium taurocholate (TC) and taurodeoxycholate (TDC) in an isotonic sodium chloride solution at 298.2 K using frontal derivative chromatography on Sephadex G-10 columns. Quantitative analysis was based on different aggregation models. Results indicate that the stepwise models for the self-association of TC and TDC are more rigorous than others.