Comparison of breeding strategies for purgin inbreeding depression via simulation

Computer simulation can be used to identify deleterious genes to be purged in breeding programs, especially for endangered species. Simulation compared continuous selfing, half-sib mating, and three mixtures of the previous two techniques as applied over 10 generations. Continuous selfing showed quick results, though without a high probability of extinction, and there were similar results for continuous half-sib mating. The most effective results used mild inbreeding.