Antagonism of PPAR-[gamma] signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis

Authors :: Guo, Bin
Huang, Xinxin
Lee, Man Ryul
Lee, Sang A
Broxmeyer, Hal E
Source :: Nature Medicine. March, 2018, Vol. 24 Issue 3, p360, 8 p.
Publication Year :: 2018
Abstract: Author(s): Bin Guo [1]; Xinxin Huang [1]; Man Ryul Lee [2]; Sang A Lee [2]; Hal E Broxmeyer (corresponding author) [1] Hematopoietic stem cells (HSCs) quiescently reside in bone marrow [...]

Subjects :: Cancer treatment -- Innovations
Hematopoietic stem cell transplantation -- Methods -- Patient outcomes
Cellular signal transduction -- Genetic aspects -- Health aspects
Transcription factors -- Health aspects
Gene expression -- Health aspects
Biological sciences
Health

Full Text Access

Tools