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Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs
- Source :
- Journal of Autism and Developmental Disorders. August, 2017, Vol. 47 Issue 8, p2621, 7 p.
- Publication Year :
- 2017
-
Abstract
- Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother's weight gain during pregnancy, maternal viral/bacterial infection and use of antibiotics, duration of breastfeeding, mode of delivery, birth weight and child GI problems. ASD was associated with GI problems and perinatal environmental risk, based on a summation of maternal infection and antibiotic use during pregnancy and/or the breastfeeding period. The association between GI problems and ASD remained within the sibling pairs ([beta] = 1.23; p < .001) in the adjusted model. Our results indicate non-shared environmental effects on the ASD/GI association, but none of the factors examined explained the link.<br />Author(s): Johan Isaksson [sup.1] [sup.2] [sup.3] , Erik Pettersson [sup.4] , Elzbieta Kostrzewa [sup.1] , Rochellys Diaz Heijtz [sup.5] , Sven Bölte [sup.1] [sup.6] Author Affiliations: (1) Department of Women's [...]
Details
- Language :
- English
- ISSN :
- 01623257
- Volume :
- 47
- Issue :
- 8
- Database :
- Gale General OneFile
- Journal :
- Journal of Autism and Developmental Disorders
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.498512226
- Full Text :
- https://doi.org/10.1007/s10803-017-3169-2