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Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2

Authors :
Liu, Zhen
Li, Xiao
Zhang, Jun-Tao
Cai, Yi-Jun
Cheng, Tian-Lin
Cheng, Cheng
Wang, Yan
Zhang, Chen-Chen
Nie, Yan-Hong
Chen, Zhi-Fang
Bian, Wen-Jie
Zhang, Ling
Xiao, Jianqiu
Lu, Bin
Zhang, Aue-fang
Zhang, Xiao-Di
Sang, Xiao
Wu, Jia-Jia
Xu, Xiu
Xiong, Zhi-Qi
Zhang, Feng
Yu, Xiang
Gong, Neng
Zhou, Wen-Hao
Sun, Qiang
Qiu, Zilong
Source :
Nature. February 4, 2016, p98, 18 p.
Publication Year :
2016

Abstract

Methyl-CpG binding protein 2 (MeCP2) has crucial roles in transcriptional regulation and microRNA processing (1-4). Mutations in the MECP2 gene are found in 90% of patients with Rett syndrome, a [...]

Details

Language :
English
ISSN :
00280836
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.442536425