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PVT1 dependence in cancer with MYC copy-number increase

Authors :
Tseng, Yuen-Yi
Moriarity, Branden S.
Gong, Wuming
Akiyama, Ryutaro
Tiwari, Ashutosh
Kawakami, Hiroko
Ronning, Peter
Reuland, Brian
Guenther, Kacey
Beadnell, Thomas C.
Essig, Jaclyn
Otto, George M.
O'Sullivan, M. Gerard
Largaespada, David A.
Schwertfeger, Kathryn L.
Marahrens, York
Kawakami, Yasuhiko
Bagchi, Anindya
Source :
Nature. August 7, 2014, Vol. 512 Issue 7512, p82, 18 p.
Publication Year :
2014

Abstract

'Gain' of supernumerary copies of the 8q24.21 chromosomal region has been shown to be common in many human cancers (1-13) and is associated with poor prognosis (7,10,14). The well-characterized myelocytomatosis [...]

Details

Language :
English
ISSN :
00280836
Volume :
512
Issue :
7512
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.377862215