Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

Authors :: Mayer-Barber, Katrin D.
Andrade, Bruno B.
Oland, Sandra D.
Amaral, Eduardo P.
Barber, Daniel L.
Gonzales, Jacqueline
Derrick, Steven C.
Shi, Ruiru
Kumar, Nathella Pavan
Wei, Wang
Yuan, Xing
Zhang, Guolong
Cai, Ying
Babu, Subash
Catalfamo, Marta
Salazar, Andres M.
Via, Laura E.
Barry, III, Clifton E.
Sher, Alan
Source :: Nature. July 3, 2014, Vol. 511 Issue 7507, p99, 17 p.
Publication Year :: 2014
Abstract: Tuberculosis remains second only to HIV/AIDS as the leading cause of mortality worldwide due to a single infectious agent (1). Despite chemotherapy, the global tuberculosis epidemic has intensified because of [...]

Subjects :: Interferon -- Dosage and administration -- Research
Tuberculosis -- Research -- Prevention -- Risk factors -- Drug therapy -- Patient outcomes
Biological response modifiers -- Research
Interleukins -- Research
Environmental issues
Science and technology
Zoology and wildlife conservation

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