New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

Authors :: Bullen, C Korin
Laird, Gregory M.
Durand, Christine M.
Siliciano, Janet D.
Siliciano, Robert F.
Source :: Nature Medicine. April 1, 2014, p425, 6 p.
Publication Year :: 2014
Abstract: HIV-1 persists in a latent reservoir despite antiretroviral therapy (ART) (1-5). This reservoir is the major barrier to HIV-1 eradication (6), (7). Current approaches to purging the latent reservoir involve [...]

Subjects :: Highly active antiretroviral therapy -- Physiological aspects -- Genetic aspects -- Research
HIV infection -- Development and progression -- Drug therapy -- Research
Biological sciences
Health

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