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An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia
- Source :
- Nature Medicine. April 1, 2014, p398, 12 p.
- Publication Year :
- 2014
-
Abstract
- The pathophysiology of ineffective erythropoiesis in b-thalassemia is poorly understood. We report that RAP-011, an activin receptor IIA (ActRIIA) ligand trap, improved ineffective erythropoiesis, corrected anemia and limited iron overload [...]
Details
- Language :
- English
- ISSN :
- 10788956
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.369247846