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HIV-1 persistence in C[D4.sup.+] T cells with stem cell--like properties

Authors :
Buzon, Maria J.
Sun, Hong
Li, Chun
Shaw, Amy
Seiss, Katherine
Ouyang, Zhengyu
Martin-Gayo, Enrique
Leng, Jin
Henrich, Timothy J.
Li, Jonathan Z.
Pereyra, Florencia
Zurakowski, Ryan
Walker, Bruce D.
Rosenberg, Eric S.
Yu, Xu G.
Lichterfeld, Mathias
Source :
Nature Medicine. February 1, 2014, Vol. 20 Issue 2, p139, 6 p.
Publication Year :
2014

Abstract

Cellular HIV-1 reservoirs that persist despite antiretroviral treatment are incompletely defined. We show that during suppressive antiretroviral therapy, [CD4.sup.+] T memory stem [cells (T.sub.SCM] cells) harbor high per-cell levels of [...]

Details

Language :
English
ISSN :
10788956
Volume :
20
Issue :
2
Database :
Gale General OneFile
Journal :
Nature Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.360205987