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Spontaneous generation of infectious prion disease in transgenic mice

Authors :
Torres, Juan-Maria
Castilla, Joaquin
Pintado, Belen
Gutierrez-Adan, Alfonso
Andreoletti, Olivier
Aguilar-Calvo, Patricia
Arroba, Ana-Isabel
Parra-Arrondo, Beatriz
Ferrer, Isidro
Manzanares, Jorge
Espinosa, Juan-Carlos
Source :
Emerging Infectious Diseases. December 1, 2013, Vol. 19 Issue 12, p1938, 10 p.
Publication Year :
2013

Abstract

Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases that affect humans and animals and involve pathologic conversion of host cellular prion protein ([PrP.sup.C]) to a disease-related isoform ([PrP.sup.Sc]), as proposed [...]

Details

Language :
English
ISSN :
10806040
Volume :
19
Issue :
12
Database :
Gale General OneFile
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsgcl.356142841
Full Text :
https://doi.org/10.3201/eid1912.130106