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CD28 and ITK signals regulate autoreactive T cell trafficking
- Source :
- Nature Medicine. December 1, 2013, Vol. 19 Issue 12, p1612, 8 p.
- Publication Year :
- 2013
-
Abstract
- Activation of self-reactive T cells and their trafficking to target tissues leads to autoimmune organ destruction. Mice lacking the co-inhibitory receptor cytotoxic T lymphocyte antigen-4 (CTLA-4) develop fatal autoimmunity characterized [...]
Details
- Language :
- English
- ISSN :
- 10788956
- Volume :
- 19
- Issue :
- 12
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.353323177
- Full Text :
- https://doi.org/10.1038/nm.3393