Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein

Authors :: Wadsworth, Jonathan D.F.
Joiner, Susan
Linehan, Jacqueline M.
Balkema-Buschmann, Anne
Spiropoulos, John
Simmons, Marion M.
Griffiths, Peter C.
Groschup, Martin H.
Hope, James
Brandner, Sebastian
Asante, Emmanuel A.
Collinge, John
Source :: Emerging Infectious Diseases. November 1, 2013, Vol. 19 Issue 11, p1731, 9 p.
Publication Year :: 2013
Abstract: Bovine spongiform encephalopathy (BSE) is the transmissible spongiform encephalopathy (TSE) or prion disease of domestic cattle. The BSE prion is an epizootic agent and causes variant Creutzfeldt-Jakob disease (vCJD) in [...]

Subjects :: Prions -- Research -- Genetic aspects
Bovine spongiform encephalopathy -- Research -- Genetic aspects
Animal experimentation -- Usage
Health

Full Text Access

Tools