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Tumor adaptation and resistance to RAF inhibitors
- Source :
- Nature Medicine. November 1, 2013, Vol. 19 Issue 11, p1401, 9 p.
- Publication Year :
- 2013
-
Abstract
- RAF kinase inhibitors have substantial therapeutic effects in patients with BRAF-mutant melanoma. However, only rarely do tumors regress completely, and the therapeutic effects are often temporary. Several mechanisms of resistance [...]
Details
- Language :
- English
- ISSN :
- 10788956
- Volume :
- 19
- Issue :
- 11
- Database :
- Gale General OneFile
- Journal :
- Nature Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.349905524
- Full Text :
- https://doi.org/10.1038/nm.3392