The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

Authors :: Zhang, Qing-Jun
Chen, Hou-Zao
Wang, Lin
Liu, De-Pei
Hill, Joseph A.
Liu, Zhi-Ping
Source :: Journal of Clinical Investigation. June 1, 2011, Vol. 121 Issue 6, p2447, 10 p.
Publication Year :: 2011
Abstract: Cardiac hypertrophy and failure are accompanied by a reprogramming of gene expression that involves transcription factors and chromatin remodeling enzymes. Little is known about the roles of histone methylation and [...]

Subjects :: Methylation
Heart enlargement
Genetic transcription
Heart
Health care industry

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