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Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

Authors :
Rotger, Margalida
Dalmau, Judith
Rauch, Andri
McLaren, Paul
Bosinger, Steven E.
Martinez, Raquel
Sandler, Netanya G.
Roque, Annelys
Liebner, Julia
Battegay, Manuel
Bernasconi, Enos
Descombes, Patrick
Erkizia, Itziar
Fellay, Jacques
Hirschel, Bernard
Miro, Jose M.
Palou, Eduard
Hoffmann, Matthias
Massanella, Marta
Blanco, Julia
Woods, Matthew
Gunthard, Huldrych F.
de Bakker, Paul
Douek, Daniel C.
Silvestri, Guido
Martinez-Picado, Javier
Telenti, Amalio
Source :
Journal of Clinical Investigation. June 1, 2011, Vol. 121 Issue 6, p2391, 10 p.
Publication Year :
2011

Abstract

High levels of HIV-1 replication during the chronic phase of infection usually correlate with rapid progression to severe immunodeficiency. However, a minority of highly viremic individuals remains asymptomatic and maintains [...]

Details

Language :
English
ISSN :
00219738
Volume :
121
Issue :
6
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.348997216
Full Text :
https://doi.org/10.1172/JCI45235