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T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung

Authors :
Piet, Berber
de Bree, Godelieve J.
Smids-Dierdorp, Barbara S.
van der Loos, Chris M.
Remmerswaal, Ester B.M.
von der Thusen, Jan H.
van Haarst, Jan M.W.
Eerenberg, Jan P.
Brinke, Anja ten
van der Bij, Wim
Timens, Wim
van Lier, Rene A.W.
Jonkers, Rene E.
Source :
Journal of Clinical Investigation. June 1, 2011, Vol. 121 Issue 6, p2254, 10 p.
Publication Year :
2011

Abstract

The human lung T cell compartment contains many [CD8.sup.+] T cells specific for respiratory viruses, suggesting that the lung is protected from recurring respiratory infections by a resident T cell [...]

Details

Language :
English
ISSN :
00219738
Volume :
121
Issue :
6
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.348997204
Full Text :
https://doi.org/10.1172/JCI44675