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The human visual cortex responds to gene therapy--mediated recovery of retinal function

Authors :
Ashtari, Manzar
Cyckowski, Laura L.
Monroe, Justin F.
Marshall, Kathleen A.
Chung, Daniel C.
Auricchio, Alberto
Simonelli, Francesca
Leroy, Bart P.
Maguire, Albert M.
Shindler, Kenneth S.
Bennett, Jean
Source :
Journal of Clinical Investigation. June 1, 2011, Vol. 121 Issue 6, p2160, 9 p.
Publication Year :
2011

Abstract

Leber congenital amaurosis (LCA) is a rare degenerative eye disease, linked to mutations in at least 14 genes. A recent gene therapy trial in patients with LCA2, who have mutations [...]

Details

Language :
English
ISSN :
00219738
Volume :
121
Issue :
6
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.348997197
Full Text :
https://doi.org/10.1172/JCI57377