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TGF-β upregulates miR-181a expression to promote breast cancer metastasis

Authors :
Taylor, Molly A.
Sossey-Alaoui, Khalid
Thompson, Cheryl L.
Danielpour, David
Schiemann, William P.
Source :
Journal of Clinical Investigation. January 1, 2013, Vol. 123 Issue 1, p150, 14 p.
Publication Year :
2013

Abstract

Late-stage breast cancer metastasis is driven by dysregulated TGF-β signaling, but the underlying molecular mechanisms have not been fully elucidated. We attempted to recapitulate tumor and metastatic micro-environments via the [...]

Subjects

Subjects :
Gene expression -- Physiological aspects -- Research
Metastasis -- Research
Apoptosis -- Research -- Physiological aspects
Breast cancer -- Research -- Causes of -- Complications and side effects
Health care industry

Details

Language :
English
ISSN :
00219738
Volume :
123
Issue :
1
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.348997145
Full Text :
https://doi.org/10.1172/JCI64946
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