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Transcription factor EGR1 directs tendon differentiation and promotes tendon repair

Authors :
Guerquin, Marie-Justine
Charvet, Benjamin
Nourissat, Geoffroy
Havis, Emmanuelle
Ronsin, Olivier
Bonnin, Marie-Ange
Ruggiu, Mathilde
Olivera-Martinez, Isabel
Robert, Nicolas
Lu, Yinhui
Kadler, Karl E.
Baumberger, Tristan
Doursounian, Levon
Berenbaum, Francis
Duprez, Delphine
Source :
Journal of Clinical Investigation. August 1, 2013, Vol. 123 Issue 8, p3564, 13 p.
Publication Year :
2013

Abstract

Tendon formation and repair rely on specific combinations of transcription factors, growth factors, and mechanical parameters that regulate the production and spatial organization of type I collagen. Here, we investigated [...]

Details

Language :
English
ISSN :
00219738
Volume :
123
Issue :
8
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.341937547
Full Text :
https://doi.org/10.1172/JCI67521