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HDAC3 is essential for DNA replication in hematopoietic progenitor cells
- Source :
- Journal of Clinical Investigation. July 1, 2013, Vol. 123 Issue 7, p3112, 12 p.
- Publication Year :
- 2013
-
Abstract
- Histone deacetylase 3 (HDAC3) contributes to the regulation of gene expression, chromatin structure, and genomic stability. Because HDAC3 associates with oncoproteins that drive leukemia and lymphoma, we engineered a conditional [...]
Details
- Language :
- English
- ISSN :
- 00219738
- Volume :
- 123
- Issue :
- 7
- Database :
- Gale General OneFile
- Journal :
- Journal of Clinical Investigation
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.341937500
- Full Text :
- https://doi.org/10.1172/JCI60806