Back to Search Start Over

Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans

Authors :
Gonzales, Jon C.
Gordts, Philip L.S.M.
Foley, Erin M.
Esko, Jeffrey D.
Source :
Journal of Clinical Investigation. June 1, 2013, Vol. 123 Issue 6, p2742, 10 p.
Publication Year :
2013

Abstract

The heparan sulfate proteoglycan (HSPG) syndecan-1 (SDC1) acts as a major receptor for triglyceride-rich lipoprotein (TRL) clearance in the liver. We sought to identify the relevant apolipoproteins on TRLs that [...]

Subjects

Subjects :
Physiological aspects
Development and progression
Genetic aspects
Research
Risk factors
Atherosclerosis -- Risk factors -- Development and progression -- Genetic aspects -- Research
Proteoglycans -- Physiological aspects -- Genetic aspects -- Research
Apolipoproteins -- Physiological aspects -- Genetic aspects -- Research

Details

Language :
English
ISSN :
00219738
Volume :
123
Issue :
6
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.341937461
Full Text :
https://doi.org/10.1172/JCI67398
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details